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What Women Should Know About the Viral NAD+ Trend

NAD+—short for nicotinamide adenine dinucleotide—has become the latest wellness obsession sweeping TikTok, wellness clinics, and celebrity circles. If you’ve seen influencers getting IV drips or taking daily pills promising boundless energy, glowing skin, and “anti-aging” magic, you’ve likely stumbled into NAD territory.

But what exactly is NAD+, does it live up to the hype, and is it safe—especially for women? Let’s break it down.

What Is NAD+ and Why Is Everyone Talking About It?

DNA.
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NAD+ is a molecule your body already makes. It’s essential for turning the food you eat into energy, repairing damaged DNA, and keeping your cells functioning properly. But here’s the catch: as we age, NAD+ levels decline—sharply. Some researchers suggest this drop may be linked to fatigue, slower metabolism, and visible signs of aging.

Enter: supplements and IV drips claiming to replenish your NAD+ levels and restore your vitality.

Who’s Taking It?

Hailey Bieber.
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This once-obscure science is now a full-blown social media phenomenon. On TikTok, #NAD has over 60 million views. Hailey Bieber, Kendall Jenner, and other wellness trendsetters reportedly use NAD+ IV infusions as part of their longevity and skincare routines. Biohackers swear by NAD supplements like NR (nicotinamide riboside) and NMN (nicotinamide mononucleotide) for sharper focus, better sleep, and improved skin.

 Does It Actually Work?

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Let’s start with what we do know:

  • Yes, NAD+ boosters can increase NAD levels in your body. That’s been proven in multiple clinical trials.
  • Benefits vary depending on your age, health, and lifestyle. People over 40 or those with metabolic issues may see more impact than young, healthy individuals.

Potential Benefits

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  • Increased energy and stamina
  • Improved muscle recovery
  • Enhanced skin health and elasticity
  • Better sleep and cognitive performance
  • Support for healthy aging and DNA repair

The science is still early-stage, but promising. Animal studies show strong anti-aging effects, and human trials—though limited—suggest improved insulin sensitivity, reduced inflammation, and improved mitochondrial function (aka your body’s energy production). However, most of these benefits appear in older or at-risk populations.

Pills, Powders, or IV Drips?

woman pouring pills from bottle.
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There are three main ways people are trying to boost their NAD+:

  1. NR and NMN Supplements (Oral)
    Available in capsule form. Widely considered safe, with doses between 250–1,000 mg per day. NMN was recently paused for supplement sale in the U.S. while the FDA reviews it as a potential drug—though it’s still available in many countries.
  2. NAD+ IV Therapy
    Clinics offer pricey infusions—often over $500 per session. Promoted for quick energy boosts or post-travel fatigue, but the FDA hasn’t approved NAD+ IVs for any medical condition.
  3. Topical NAD+ (Creams or Serums)
    Skincare brands are now adding NAD+ or precursors to anti-aging lines. The jury’s still out on effectiveness.

What to Watch Out For

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While NAD+ is generally safe, there are important caveats:

  • Beware of hype. There’s no miracle molecule. NAD+ might support healthy aging, but it won’t replace good sleep, a balanced diet, exercise, and sunscreen.
  • High doses can cause side effects. These may include nausea, headaches, or flushing. Long-term safety at high doses (especially for IV use) isn’t fully known.
  • IV drips are unregulated and expensive. You’re not getting more benefits from them than oral supplements—just a faster delivery at 10x the price.
  • Not a cure-all. If you’re experiencing fatigue, brain fog, or skin issues, don’t assume NAD+ is the solution. Rule out underlying health issues first.

Should You Try It?

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If you’re over 40, feeling sluggish, or navigating perimenopause, NAD+ might be worth exploring—with your doctor’s guidance. You may see subtle gains in energy, skin clarity, or mental sharpness.

If you’re younger and healthy, the benefits are less clear. You might not notice much unless you’re burning the candle at both ends—and even then, lifestyle changes should come first.

Quick FAQs

FDA.
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  • Is NAD+ FDA-approved?
    NR has “GRAS” status (generally recognized as safe). NMN is under FDA drug review. IV infusions are not FDA-approved.
  • Are NAD supplements safe?
    In general, yes—but start with lower doses and always consult your doctor first.
  • Where can I get it?
    Trusted supplement brands include Tru Niagen (NR) and Elysium Basis. Be cautious of unregulated online sellers.
  • Can I boost NAD naturally?
    Yes! Exercise, intermittent fasting, and a diet rich in niacin (vitamin B3) may help.

Final Thoughts from The Queen Zone

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At The Queen Zone, we love exploring science-backed strategies to feel strong, sharp, and ageless. But we also believe wellness shouldn’t be ruled by expensive trends and celebrity endorsements.

NAD+ isn’t a scam—but it’s also not a shortcut. Use it as a supplement, not a substitute, for habits that nourish you inside and out. And before you book that trendy IV drip or buy a $100 bottle of NMN, ask yourself: have you slept, moved, hydrated, and laughed today?

That’s the real longevity plan.

Shop trusted NAD here:

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 10 Things Dermatologists Never Do to Their Skin—And You Shouldn’t Either

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Kmpzzz via Shutterstock.

READ: 10 Things Dermatologists Never Do to Their Skin—And You Shouldn’t Either

Dermatologists know skin inside and out—literally. While most of us are busy trying the latest trends or TikTok hacks, skin doctors are quietly sticking to proven habits and steering clear of the very things that can damage or prematurely age skin. Ever wonder what a dermatologist avoids like the plague? It turns out they skip quite a few things the average person might think are harmless, or even helpful. If you want healthier, glowier, and more resilient skin, here are 10 things they never do—and why you shouldn’t either.

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Author

  • Robin Jaffin headshot circle

    Robin Jaffin is a strategic communicator and entrepreneur dedicated to impactful storytelling, environmental advocacy, and women's empowerment. As Co-Founder of The Queen Zone™, Robin amplifies women's diverse experiences through engaging multimedia content across global platforms. Additionally, Robin co-founded FODMAP Everyday®, an internationally recognized resource improving lives through evidence-based health and wellness support for those managing IBS. With nearly two decades at Verité, Robin led groundbreaking initiatives promoting human rights in global supply chains.

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Last update on 2025-06-26 / Affiliate links / Images from Amazon Product Advertising API

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